Slug Expression in the E-cadherin preserved tumors is related to prognosis in patients with esophageal squamous cell carcinoma.

@article{Uchikado2005SlugEI,
  title={Slug Expression in the E-cadherin preserved tumors is related to prognosis in patients with esophageal squamous cell carcinoma.},
  author={Yasuto Uchikado and Shoji Natsugoe and Hiroshi Okumura and Tetsuro Setoyama and Masataka Matsumoto and Sumiya Ishigami and Takashi Aikou},
  journal={Clinical cancer research : an official journal of the American Association for Cancer Research},
  year={2005},
  volume={11 3},
  pages={1174-80}
}
PURPOSE The expression of E-cadherin correlates with the development, progression, and metastasis of esophageal squamous cell carcinoma (ESCC). Slug, a member of the snail family of transcriptional factors, is a newly identified suppressive transcriptional factor of E-cadherin. The purpose of the present study was to evaluate the clinical significance of E-cadherin and Slug expression in ESCC. EXPERIMENTAL DESIGN Immunohistochemistry was used to investigate the expression of E-cadherin and… CONTINUE READING

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