Slowing the deterioration of asthma and chronic obstructive pulmonary disease observed during bronchodilator therapy by adding inhaled corticosteroids. A 4-year prospective study.

@article{Dompeling1993SlowingTD,
  title={Slowing the deterioration of asthma and chronic obstructive pulmonary disease observed during bronchodilator therapy by adding inhaled corticosteroids. A 4-year prospective study.},
  author={Edward Dompeling and Constant Paul van Schayck and P. M. van Grunsven and C. L. A. van Herwaarden and Reinier Akkermans and Johan Molema and Hans T. M. Folgering and Chris van Weel},
  journal={Annals of internal medicine},
  year={1993},
  volume={118 10},
  pages={770-8}
}
OBJECTIVE To determine if deterioration in patients with asthma or chronic obstructive pulmonary disease (COPD) during bronchodilator therapy could be slowed by additional treatment with an inhaled corticosteroid. DESIGN A 4-year prospective study. SETTING Twenty-nine general practices in the catchment area of the University of Nijmegen, Nijmegen, the Netherlands. PATIENTS The study included 56 patients (28 with asthma and 28 with COPD) who showed an annual decrease in the forced… CONTINUE READING
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