Slowing of peripheral motor nerve conduction was ameliorated by aminoguanidine in streptozocin-induced diabetic rats.

@article{Miyauchi1996SlowingOP,
  title={Slowing of peripheral motor nerve conduction was ameliorated by aminoguanidine in streptozocin-induced diabetic rats.},
  author={Yoshimasa Miyauchi and Hisataka Shikama and Toshiyuki Takasu and Hideaki Okamiya and Masakazu Umeda and Eishi Hirasaki and I. Ohhata and Haruyuki Nakayama and Shizue Nakagawa},
  journal={European journal of endocrinology},
  year={1996},
  volume={134 4},
  pages={467-73}
}
The aims of this study were to investigate the effect of aminoguanidine (AG) on slowing of motor nerve conduction velocity (MNCV) of the sciatic nerve in streptozocin-induced diabetic rats and to assess its mechanism of action. The MNCV of the sciatic nerve was measured electrophysiologically in diabetic rats treated with and without AG for 16 weeks. To elucidate the action of AG, morphological lesion and abnormality of polyol pathway metabolism in the nerve were examined and tissue levels of… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 14 extracted citations

Diabetic Microvascular Disease: An Endocrine Society Scientific Statement.

The Journal of clinical endocrinology and metabolism • 2017
View 1 Excerpt

Update on the management of diabetic polyneuropathies

Diabetes, metabolic syndrome and obesity : targets and therapy • 2011
View 1 Excerpt

Diabetic Renal-Retinal Syndrome

Springer Netherlands • 2002

Similar Papers

Loading similar papers…