Slow volume transients in amphibian skeletal muscle fibres studied in hypotonic solutions.

@article{Fraser2005SlowVT,
  title={Slow volume transients in amphibian skeletal muscle fibres studied in hypotonic solutions.},
  author={James A Fraser and Catherine Elizabeth Jule Rang and Juliet A Usher-Smith and Christopher L.-H. Huang},
  journal={The Journal of physiology},
  year={2005},
  volume={564 Pt 1},
  pages={51-63}
}
The influence of extracellular hypotonicity on the relationship between cell volume (V(c)) and resting membrane potential (E(m)) was investigated in Rana temporaria skeletal muscle. V(c) was measured by confocal microscope imaging of fibres through their transverse (xz) planes, and E(m) was determined using standard microelectrode techniques. Hypotonic solutions first elicited a rapid increase in fibre volume, DeltaV(R+) that fulfilled expectations of simple osmotic behaviour described in… CONTINUE READING