Slow phasic and tonic activity of ventral pallidal neurons during cocaine self-administration.

@article{Root2012SlowPA,
  title={Slow phasic and tonic activity of ventral pallidal neurons during cocaine self-administration.},
  author={David H Root and Anthony T. Fabbricatore and Anthony P. Pawlak and David J. Barker and Sisi Ma and Mark O. West},
  journal={Synapse},
  year={2012},
  volume={66 2},
  pages={106-27}
}
Ventral pallidal (VP) neurons exhibit rapid phasic firing patterns within seconds of cocaine-reinforced responses. The present investigation examined whether VP neurons exhibited firing rate changes: (1) over minutes during the inter-infusion interval (slow phasic patterns) and/or (2) over the course of the several-hour self-administration session (tonic firing patterns) relative to pre-session firing. Approximately three-quarters (43/54) of VP neurons exhibited slow phasic firing patterns. The… CONTINUE READING