Slow oscillations in two pairs of dopaminergic neurons gate long-term memory formation in Drosophila

@article{Plaais2012SlowOI,
  title={Slow oscillations in two pairs of dopaminergic neurons gate long-term memory formation in Drosophila},
  author={Pierre-Yves Plaçais and S{\'e}verine Trannoy and Guillaume Isabel and Yoshinori Aso and Igor Siwanowicz and Ghislain Belliart-Gu{\'e}rin and Philippe Vernier and Serge Birman and Hiromu Tanimoto and Thomas Pr{\'e}at},
  journal={Nature Neuroscience},
  year={2012},
  volume={15},
  pages={592-599}
}
A fundamental duty of any efficient memory system is to prevent long-lasting storage of poorly relevant information. However, little is known about dedicated mechanisms that appropriately trigger production of long-term memory (LTM). We examined the role of Drosophila dopaminergic neurons in the control of LTM formation and found that they act as a switch between two exclusive consolidation pathways leading to LTM or anesthesia-resistant memory (ARM). Blockade, after aversive olfactory… CONTINUE READING
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