Slow conductances in neurons from cat sensorimotor cortex in vitro and their role in slow excitability changes.

@article{Schwindt1988SlowCI,
  title={Slow conductances in neurons from cat sensorimotor cortex in vitro and their role in slow excitability changes.},
  author={Peter C. Schwindt and William J. Spain and Robert C. Foehring and M C Chubb and Wayne E. Crill},
  journal={Journal of neurophysiology},
  year={1988},
  volume={59 2},
  pages={450-67}
}
1. The electrophysiological and pharmacological properties of slow afterpotentials in large layer V neurons from cat sensorimotor cortex were studied in an in vitro slice preparation using intracellular recording and single-microelectrode voltage clamp. These properties were used to assess the role of afterpotential mechanisms in prolonged excitability changes. 2. The mean duration of a slow afterhyperpolarization (sAHP) was 13.5 s following 100 spikes evoked at 100 Hz. Its time course was best… CONTINUE READING
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