Slow and rapid psychobiological alterations in a manic-depressive patient: clinical phenomenology.

Abstract

A distinctive pattern of clinical change during eight affective episodes is reported in a rapidly cycling manic-depressive patient. After a rapid switch to near maximal intensity of affective symptoms, slow changes in symptomatology were documented by significant slopes and correlation coefficients over the course of each episode. Decreases in depression… (More)

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@article{Stoddard1977SlowAR, title={Slow and rapid psychobiological alterations in a manic-depressive patient: clinical phenomenology.}, author={Frederick J Stoddard and Robert Post and William E. Bunney}, journal={The British journal of psychiatry : the journal of mental science}, year={1977}, volume={130}, pages={72-8} }