Slow, medium, or fast re-warming following post-traumatic hypothermia therapy? An ultrastructural perspective.

@article{Maxwell2005SlowMO,
  title={Slow, medium, or fast re-warming following post-traumatic hypothermia therapy? An ultrastructural perspective.},
  author={William L. Maxwell and Anna Watson and Ross Queen and Bernard A. Conway and David Russell and Matt Neilson and David I. Graham},
  journal={Journal of neurotrauma},
  year={2005},
  volume={22 8},
  pages={873-84}
}
It was hypothesized that rapid rather than slow re-warming following traumatic brain injury (TBI) and short-term hypothermia results in secondary, ultrastructural pathology. After stretch injury to the right optic nerve, adult guinea pigs were randomly allocated to one of six experimental groups. Either (1) sham (all procedures but not stretch-injured; n = 4); injured and (2) maintained at normal temporalis core temperature (38.5 degrees C) for 8 hours (n = 6); (3) cooled rapidly to 32.5… CONTINUE READING