Slit and glypican-1 mRNAs are coexpressed in the reactive astrocytes of the injured adult brain.

@article{Hagino2003SlitAG,
  title={Slit and glypican-1 mRNAs are coexpressed in the reactive astrocytes of the injured adult brain.},
  author={Seita Hagino and Ken Iseki and Tetsuji Mori and Yuxiang Zhang and Tsuyoshi Hikake and Sachihiko Yokoya and Mayumi Takeuchi and Hiromi Hasimoto and Shinichi Kikuchi and Akio Wanaka},
  journal={Glia},
  year={2003},
  volume={42 2},
  pages={130-8}
}
The slit family serves as a repellent for growing axons toward correct targets during neural development. A recent report describes slit mRNAs expressed in various brain regions in adult rats. However, their functions in the adult nervous system remain unknown. In the present study, we investigated whether slit mRNAs were expressed in the cryo-injured brain, using in situ hybridization. All slit family members were expressed at the lesion. Slit2 mRNA was the most intensely expressed in the… CONTINUE READING

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