Sleeping Sickness Epidemics and Colonial Responses in East and Central Africa, 1900–1940

@article{Headrick2014SleepingSE,
  title={Sleeping Sickness Epidemics and Colonial Responses in East and Central Africa, 1900–1940},
  author={Daniel R. Headrick},
  journal={PLoS Neglected Tropical Diseases},
  year={2014},
  volume={8}
}
  • D. Headrick
  • Published 1 April 2014
  • History
  • PLoS Neglected Tropical Diseases
In the early 20th centu- ry, major epidemics of trypanoso- miasis (sleeping sickness) broke out in East and Central Africa. The European colonial powers that controlled this area reacted by sending scientific missions to study the disease, establishing schools of tropical medicine, testing drugs, and instituting measures to eradi- cate the epidemic. Several very distinct approaches were taken to this end. German efforts focused on developing and testing new drugs, but were hampered by a lack of… 

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References

SHOWING 1-10 OF 96 REFERENCES

Ecologies of Complexity: Tropical Environments, African Trypanosomiasis, and the Science of Disease Control in British Colonial Africa, 1900-1940

TLDR
The history of British attempts to understand and control African trypanosomiasis, following the intense human epidemics that broke out between 1895 and 1910, reveals hitherto ignored scientific research in the fields of ecology, epidemiology, and tropical medicine that helped produce a new understanding of the "ecology of disease".

History of Sleeping Sickness in East Africa

  • G. Hide
  • Biology
    Clinical Microbiology Reviews
  • 1999
TLDR
The contribution of molecular and genetic data to the understanding of the epidemiology and history of human sleeping sickness in East Africa is examined to highlight the important factors involved in the generation of epidemics.

History of sleeping sickness (African trypanosomiasis).

  • F. Cox
  • Medicine
    Infectious disease clinics of North America
  • 2004

Reanalyzing the 1900-1920 sleeping sickness epidemic in Uganda.

TLDR
Analysis of clinical data recorded in the early 1900s shows that the clinical course of sleeping sickness cases during the 1900-1920 epidemic in Uganda was markedly different from T.b. gambiense cases, but similar to T. b.

Bacteria or parasite? the controversy over the etiology of sleeping sickness and the Portuguese participation, 1898-1904.

  • I. Amaral
  • History
    Historia, ciencias, saude--Manguinhos
  • 2012
TLDR
The etiology of sleeping sickness was unknown until the early twentieth century, and two British missions to study the disease in Entebbe led to a controversy in which Portugal was involved from 1898 to 1904, on the national and international circuits.

Trypanosomiasis Control in African History: An Evaded Issue?

  • J. Giblin
  • Geography
    The Journal of African History
  • 1990
Social control of trypanosomiasis in African history deserves further study. The pioneering work in this field is John Ford's respected but neglected The Role of the Trypanosomiases in African

International co-operation: past and present

Sleeping sickness is a disease of the African continent South of the Sahara. It was known amongst several tribes in Africa before Arabs and Europeans found it. The earliest written reference dates

The history of African trypanosomiasis

TLDR
Current history of human African trypanosomiasis has shown that the production of anti-sleeping sickness drugs is not always guaranteed, and therefore, new, better and cheaper drugs are urgently required.

Sleeping sickness. The Castellani-Bruce controversy

  • J. Boyd
  • History
    Notes and Records of the Royal Society of London
  • 1973
TLDR
Professor Castellani was undoubtedly the first to discover trypanosomes in the cerebro-spinal fluid of patients suffering from sleeping sickness, but there is reason to believe that he failed to appreciate the etiological significance of this finding, until it was brought home to him by Lieut.-Colonel later Colonel Sir David) Bruce.
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