Sleeping Beauty transposon system harboring HRAS, c-Myc and shp53 induces sarcomatoid carcinomas in mouse skin

@inproceedings{Jung2013SleepingBT,
  title={Sleeping Beauty transposon system harboring HRAS, c-Myc and shp53 induces sarcomatoid carcinomas in mouse skin},
  author={Sunyoung Jung and Simon Weonsang Ro and Geunyoung Jung and Hye-Lim Ju and E Q Yu and Woo-Chan Son},
  booktitle={Oncology reports},
  year={2013}
}
The Sleeping Beauty transposon system is used as a tool for insertional mutagenesis and oncogenesis. However, little is known about the exact histological phenotype of the tumors induced. Thus, we used immunohistochemical markers to enable histological identification of the type of tumor induced by subcutaneous… CONTINUE READING