Sleepiness and performance during three-day administration of cetirizine or diphenhydramine.

@article{Schweitzer1994SleepinessAP,
  title={Sleepiness and performance during three-day administration of cetirizine or diphenhydramine.},
  author={Paula K. Schweitzer and Mark J. Muehlbach and James K Walsh},
  journal={The Journal of allergy and clinical immunology},
  year={1994},
  volume={94 4},
  pages={716-24}
}
OBJECTIVE The sedative effects of cetirizine (10 mg once daily), diphenhydramine (50 mg three times daily), and placebo, each administered during a 3-day period, were compared with objective measures of sleepiness and performance. METHODS Twelve atopic subjects received each of the three treatments for 3 consecutive days in a double-blind Latin square design. Subjects received either cetirizine at 8:00 AM and placebo at 3:00 PM and 10:00 PM; diphenhydramine at 8:00 AM, 3:00 PM, and 10:00 PM… CONTINUE READING

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