Sleep spindle deficits in antipsychotic-naïve early course schizophrenia and in non-psychotic first-degree relatives

@inproceedings{Manoach2014SleepSD,
  title={Sleep spindle deficits in antipsychotic-na{\"i}ve early course schizophrenia and in non-psychotic first-degree relatives},
  author={Dara S. Manoach and Charmaine Demanuele and Erin J Wamsley and Mark E Vangel and Debra M. Montrose and Jean M Miewald and David Jerome Kupfer and Daniel Buysse and Robert Stickgold and Matcheri S. Keshavan},
  booktitle={Front. Hum. Neurosci.},
  year={2014}
}
INTRODUCTION Chronic medicated patients with schizophrenia have marked reductions in sleep spindle activity and a correlated deficit in sleep-dependent memory consolidation. Using archival data, we investigated whether antipsychotic-naïve early course patients with schizophrenia and young non-psychotic first-degree relatives of patients with schizophrenia also show reduced sleep spindle activity and whether spindle activity correlates with cognitive function and symptoms. METHOD Sleep… CONTINUE READING
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The effects of eszopiclone on sleep spindles and memory consolidation in schizophrenia : a randomized placebo - controlled trial

  • E. Wamsley, M. A. Tucker, A. K. Shinn, K. E. Ono, S. McKinley, A. V. Ely
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10.3389/fnhum.2014.00762 This article was submitted to the journal Frontiers in Human Neuroscience

  • Manoach, Demanuele, +7 authors Keshavan
  • first-degree relatives. Front. Hum. Neurosci
  • 2014

Sleep spindle deficits in antipsychotic-naïve early course schizophrenia and in non-psychotic

  • DS Citation Manoach, C Demanuele, +7 authors MS Keshavan
  • 2014

The effects of eszopiclone on sleep spindles and memory

  • 2013

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