Sleep in schizophrenic patients on and off haloperidol therapy. Clinically stable vs relapsed patients.

@article{Neylan1992SleepIS,
  title={Sleep in schizophrenic patients on and off haloperidol therapy. Clinically stable vs relapsed patients.},
  author={Thomas C. Neylan and Daniel P van Kammen and Mary E. Kelley and Jeffrey L. Peters},
  journal={Archives of general psychiatry},
  year={1992},
  volume={49 8},
  pages={643-9}
}
We examined the state-dependent contribution of neuroleptic withdrawal and psychotic relapse in influencing sleep measures. Eighteen clinically stable male schizophrenic patients taking haloperidol were studied with 3 nights of polysomnography for baseline measures and again after neuroleptic withdrawal. Sleep measures were also obtained at the point of relapse (n = 9) or after a 6-week drug-free period if the patient remained clinically stable (n = 9). Neuroleptic withdrawal led to a global… CONTINUE READING

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