Sleep in late-life recurrent depression. Changes during early continuation therapy with nortriptyline.

@article{Reynolds1991SleepIL,
  title={Sleep in late-life recurrent depression. Changes during early continuation therapy with nortriptyline.},
  author={Charles F. Reynolds and Carolyn C. Hoch and Daniel J Buysse and Charles J. George and Patricia R. Houck and Sati Mazumdar and M Miller and Bruce G. Pollock and Hilmi Rifai and Ellen Frank},
  journal={Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology},
  year={1991},
  volume={5 2},
  pages={85-96}
}
The sleep of thirty elderly patients with recurrent unipolar depression was examined at baseline (before acute treatment of the index episode) and again in a state of symptomatic remission with nortriptyline (mean steady-state level: 82.1 ng/ml). Continuation therapy with nortriptyline was associated with improvement of polysomnographic sleep maintenance… CONTINUE READING