Sleep homeostasis in Drosophila melanogaster.

@article{Huber2004SleepHI,
  title={Sleep homeostasis in Drosophila melanogaster.},
  author={R. Huber and Sean L. Hill and Carie E. Holladay and Melissa Biesiadecki and G. Tononi and C. Cirelli},
  journal={Sleep},
  year={2004},
  volume={27 4},
  pages={
          628-39
        }
}
STUDY OBJECTIVES The fruit fly Drosophila melanogaster is emerging as a promising model system for the genetic dissection of sleep. As in mammals, sleep in the fruit fly is a reversible state of reduced responsiveness to the external world and has been defined using an array of behavioral, pharmacologic, molecular, and electrophysiologic criteria. A central feature of mammalian sleep is its homeostatic regulation by the amount of previous wakefulness. Dissecting the mechanisms of homeostatic… Expand
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