Sleep-endocrine effects of mifepristone and megestrol acetate in healthy men.

@article{Wiedemann1998SleependocrineEO,
  title={Sleep-endocrine effects of mifepristone and megestrol acetate in healthy men.},
  author={K. Wiedemann and C. Lauer and M. Hirschmann and K. Knaudt and F. Holsboer},
  journal={American journal of physiology. Endocrinology and metabolism},
  year={1998},
  volume={274 1},
  pages={E139-E145}
}
  • K. Wiedemann, C. Lauer, +2 authors F. Holsboer
  • Published 1998
  • Medicine, Biology
  • American journal of physiology. Endocrinology and metabolism
  • Administration of steroid hormones was demonstrated to modulate the sleep electroencephalogram (EEG) and sleep-associated hormonal secretion in specific ways. The present study was conducted to compare the effects of mifepristone (Mif), a mixed glucocorticoid (GR) and progesterone receptor (PR) antagonist, and megestrol acetate (Meg), a PR agonist. Nine healthy men were pretreated with either placebo or 200 mg Mif or 320 mg Meg, or a combination of both. Changes in plasma adrenocorticotropic… CONTINUE READING
    Sleep and the hypothalamo-pituitary-adrenocortical system.
    • 236
    Neurochemical regulation of sleep.
    • 198

    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 41 REFERENCES