Sleep duration and depressive symptoms: a gene-environment interaction.

@article{Watson2014SleepDA,
  title={Sleep duration and depressive symptoms: a gene-environment interaction.},
  author={Nathaniel F. Watson and Kathryn Paige Harden and Dedra Buchwald and M. Vitiello and Allan I. Pack and Eric Strachan and Jack Goldberg},
  journal={Sleep},
  year={2014},
  volume={37 2},
  pages={
          351-8
        }
}
OBJECTIVE We used quantitative genetic models to assess whether sleep duration modifies genetic and environmental influences on depressive symptoms. METHOD Participants were 1,788 adult twins from 894 same-sex twin pairs (192 male and 412 female monozygotic [MZ] pairs, and 81 male and 209 female dizygotic [DZ] pairs] from the University of Washington Twin Registry. Participants self-reported habitual sleep duration and depressive symptoms. Data were analyzed using quantitative genetic… 

Figures and Tables from this paper

Sleep Duration and Area-Level Deprivation in Twins.

TLDR
Area-level deprivation has a quasi-causal association with sleep duration, with greater deprivation being related to shorter sleep, and unique genetic and nonshared environmental residual variance in sleep duration increases.

Sleep Duration and Post-Traumatic Stress Disorder Symptoms: A Twin Study.

TLDR
Shorter and longer sleep duration were associated with higher IES scores with a quadratic association, which suggests childhood experiences impact variability of sleep duration and genetic factors impact the variability of PTSD symptoms in trauma-exposed individuals.

Sleep Quality, Sleep Structure, and PER3 Genotype Mediate Chronotype Effects on Depressive Symptoms in Young Adults

TLDR
Examination of the relationships between sleep-wake chronotype, sleep disturbance, depression and genotypes associated with the PER3 variable number of tandom repeats (VNTR) polymorphism suggests that circadian gene variants may show sex-specific effects linking sleep duration and sleep structure to depression.

Association of Depressive Symptoms with Sleep Disturbance: A Co-twin Control Study.

  • M. HuangD. Bliwise V. Vaccarino
  • Psychology, Medicine
    Annals of behavioral medicine : a publication of the Society of Behavioral Medicine
  • 2021
TLDR
Depression is associated with REM sleep disruption in lab and sleep fragmentation and sleep variability at home, but not with sleep architecture or sleep-disordered breathing.

Social Integration and Sleep Disturbance: A Gene-Environment Interaction Study

Objective: Low levels of perceived social integration, or loneliness, are associated with increased risk for a range of poor health outcomes. Sleep disturbance plays a central role in the

Association between sleep duration and quality and depressive symptoms among university students: A cross-sectional study

TLDR
Poor sleep quality and short sleep duration were associated with a higher prevalence of depressive symptoms in this study population, suggesting that reduced sleep duration and quality may be risk factors for mental health disorders among university students.

Neighborhood deprivation and depression in adult twins: genetics and gene×environment interaction

TLDR
Neighborhood deprivation is an important contributor to depression via increasing the genetic risk andModifiable pathways that link neighborhoods to depression have been proposed and should serve as targets for intervention and research.

Twin Studies in Sleep Medicine: A Review

TLDR
The major findings of twin studies related to sleep are described and how they impact the understanding of this critical component of health and disease are described.

Association between Depressed Mood and Sleep Duration among Various Ethnic Groups—The Helius Study

TLDR
If confirmed in longitudinal analyses, strategies to reduce depression may reduce the prevalence of short sleep in concerned groups, including Ghanaians and Turkish, except in Dutch.
...

References

SHOWING 1-10 OF 100 REFERENCES

Sleep duration and body mass index in twins: a gene-environment interaction.

TLDR
Shorter sleep duration is associated with increased BMI and increased genetic influences on BMI, suggesting that shorter sleep duration increases expression of genetic risks for high body weight at the same time, longer sleep duration may suppress Genetic influences on body weight.

A twin study of sleep duration and body mass index.

TLDR
Short sleep was associated with elevated BMI following careful adjustment for genetics and shared environment, pointing toward an environmental cause of the relationship between sleep duration and BMI.

Genetic and environmental influences on insomnia, daytime sleepiness, and obesity in twins.

TLDR
Common genetic effects were observed between insomnia and both sleepiness and obesity, suggesting shared genetic contributions to these phenomena.

Genetic and environmental determination of human sleep.

TLDR
Self-reported sleep data from 2238 monozygotic and 4545 dizygotic adult twin pairs indicated a significant hereditary effect on sleep length and sleep quality and significant heritability estimates were found for all groups except women living together.

Short sleep as an environmental exposure: a preliminary study associating 5-HTTLPR genotype to self-reported sleep duration and depressed mood in first-year university students.

TLDR
Data indicate that young adults who reported shorter nocturnal sleep and higher depressed mood are more likely than others to carry a variant of the SLC6A4 gene associated with low expression of the serotonin transporter.

Familial influences on the clinical characteristics of major depression: a twin study

TLDR
The results suggest that familial factors influence the predisposition to some clinical features of MD, and twin resemblance for the degree of impairment and neurovegetative symptoms are probably due largely to genetic factors.

Association of sleep duration and hypertension among US adults varies by age and sex.

TLDR
The association between hours of sleep and hypertension varies by age and sex, and among adults less than 45 years, short and long sleep were associated with higher likelihood of hypertension.

Replication of Genome‐Wide association studies (GWAS) loci for sleep in the British G1219 cohort

TLDR
Findings add further support for the involvement of calcium channels in the mechanisms regulating sleep function and suggest a possible role of the ABCC9 gene in depression.

Sleep disturbance relates to neuropsychological functioning in late-life depression.

...