Sleep disorders in patients with severe mental depression: Double‐blind placebo‐controlled evaluation of the value of pipamperone (Dipiperon®)

  title={Sleep disorders in patients with severe mental depression: Double‐blind placebo‐controlled evaluation of the value of pipamperone (Dipiperon{\textregistered})},
  author={Constant Ansoms and G D Backer-Dierick and Jean Vereecken},
  journal={Acta Psychiatrica Scandinavica},
Pipamperone was compared double‐blindly with placebo to evaluate its capacity to relieve sleep disorders in 40 depressive inpatients. At the end of the 1‐week trial, most of the items relating to sleep disturbances had improved significantly in the 24 patients of the pipamperone group whereas only a few items showed such a change in the control group. On the Hamilton depression scale, improvement in the pipamperone patients was also superior to that in the placebo group as regards the items… 

Risperidone versus haloperidol in the treatment of chronic schizophrenic inpatients: a multicentre double‐blind comparative study

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A 6‐week double‐blind cross‐over study comparing pipamperone with placebo was conducted in 20 female mental retardates with behavioural disorders, finding that patients showed a better response during the pip amperone than during the placebo period.

Pipamperone (Dipiperon) in the treatment of behaviour disorders. A large-scale multicentre evaluation.

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  • Medicine, Psychology
    Acta psychiatrica Belgica
  • 1976
Pipamperone solution or tablets were prescribed for four weeks to 188 patients with behavior disorders and proved to be far superior to previous psychotropic drugs in patients who had been treated before.

Das klinische Wirkungsbild des Floropipamid. Ergebnisse mehrjahriger klinischer Untersuchungen

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[Character disorders and their treatment by pipamperone].

The treatment of chronic psychoses with dipiperon-R 3345.

  • A. Nuyts
  • Psychology
    Acta neurologica et psychiatrica Belgica
  • 1963


Pipamperone (DipipermQ R 3 345) in troublesome mental retardates. A doubleblind placebcontrolled cross-over study with long-term follow-up

  • Acta psychiat. scand
  • 1975