Sleep-disordered breathing in children is associated with impairment of sleep stage-specific shift of cardiac autonomic modulation.

@article{Liao2010SleepdisorderedBI,
  title={Sleep-disordered breathing in children is associated with impairment of sleep stage-specific shift of cardiac autonomic modulation.},
  author={Duanping Liao and Xian Li and Alexandros N. Vgontzas and Jiahao Liu and Sol M. Rodr{\'i}guez-Col{\'o}n and Susan L. Calhoun and Edward O. Bixler},
  journal={Journal of sleep research},
  year={2010},
  volume={19 2},
  pages={358-65}
}
We examined the effects of sleep stages and sleep-disordered breathing (SDB) on autonomic modulation in 700 children. Apnea hypopnea index (AHI) during one 9 h night-time polysomnography was used to define SDB. Sleep stage-specific autonomic modulation was measured by heart rate variability (HRV) analysis of the first available 5 min RR intervals from each sleep stage. The mean [standard deviation (SD)] age was 112 (21) months (49% male and 25% non-Caucasian). The average AHI was 0.79 (SD = 1… CONTINUE READING

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