Sleep deprivation in the rat by the disk-over-water method.

  title={Sleep deprivation in the rat by the disk-over-water method.},
  author={Allan Rechtschaffen and Bernard M Bergmann},
  journal={Behavioural brain research},
  volume={69 1-2},
Chronic sleep deprivation may be required to reveal the most serious physiological consequences of sleep loss, but it usually requires strong stimulation which can obscure the interpretation of effects. The disk-over-water method permits chronic sleep deprivation of rats with gentle physical stimulation that can be equally applied to yoked control rats. A series of studies with this method has revealed little or no pathology in the control rats. The deprived rats show a reliable syndrome that… CONTINUE READING
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