Sleep apnea in patients receiving growth hormone.

  title={Sleep apnea in patients receiving growth hormone.},
  author={James Matthew Gerard and Luigi Garibaldi and Susan E. Myers and Thomas Aceto and Suresh Kotagal and Veronique Gibbons and Jeffrey Stith and Christian Weber},
  journal={Clinical pediatrics},
  volume={36 6},
Among 145 patients treated with recombinant human growth hormone (GH), four developed sleep apnea (two obstructive, two mixed) associated with tonsillar and adenoidal hypertrophy in three. These four patients had no local risk factors predisposing to upper airway obstruction (i.e., frequent pharyngitis or sinusitis). Clinical and/or polysomnographic features of sleep apnea improved following cessation of GH therapy in one patient, and following tonsillectomy and adenoidectomy in all patients… CONTINUE READING