Sleep and pain sensitivity in adults

  title={Sleep and pain sensitivity in adults},
  author={B{\o}rge Sivertsen and Tea Lallukka and Keith J. Petrie and {\'O}l{\"o}f Anna Steingr{\'i}msd{\'o}ttir and Audun Stubhaug and Christopher Sivert Nielsen},
Abstract Sleep problems and pain are major public health concerns, but the nature of the association between the 2 conditions is inadequately studied. The aim of this study was to determine whether a range of sleep measures is associated with experimental increased pain sensitivity. A cross-sectional large population-based study from 2007 to 2008, the Tromsø 6 study, provided data from 10,412 participants (age: mean [SD], 58 [13] years; 54% women). Self-reported sleep measures provided… 

Pain and sleep.

It is concluded that sleep disturbances should be assessed in those with chronic painful conditions and that specific management of sleep disorders along with management of pain should be attempted to achieve synergistic improvements, as has recently been suggested for patients with sleep disturbances and osteoarthritis.

Sleep problems and pain: a longitudinal cohort study in emerging adults

Sleep problems were associated with chronic pain, musculoskeletal pain, headache and abdominal pain severity, and predicted chronic pain and an increase in musculo-knee pain severity at 3 years of follow-up.

The association of sleepiness, insomnia, sleep disturbance and pain: a study amongst shiftworking nurses

Insomnia seems to be more strongly associated with musculoskeletal pain than subjective sleepiness, thus the measures used to explore this association should be carefully selected when studying the relation between disturbed sleep and pain.

Sleep extension reduces pain sensitivity.

Sleep disturbance in patients attending specialized chronic pain clinics in Denmark: a longitudinal study examining the relationship between sleep and pain outcomes

Self-reported sleep disturbances were associated with pain outcomes at baseline and follow-up, with greater sleep disturbances associated with poorer pain outcomes, adding to a growing body of evidence confirming an association between sleep and chronic pain experience.

Sleep and Pain: the Role of Depression

The state-of-the-science of the interrelations among sleep, pain, and mood is evaluated and a growing body of research indicates that disruptions in mood may be one mechanism through which sleep disruptions are related to daytime pain.


Young athletes with lower levels of sleep quality show higher levels of pain at rest and during sports practice, and sleep quality and pain should be considered in the routine assessment of young athletes, by technical and health teams.

I'm tired and it hurts! Sleep quality and acute pain response in a chronic pain population.

Sleep and its Association With Pain and Depression in Nursing Home Patients With Advanced Dementia – a Cross-Sectional Study

When sleep was measured with actigraphy, NH patients with dementia and pain slept more than patients without pain, in terms of higher total sleep time, indicating that the patients had more sleep within the time they spent in bed.



Self-reported sleep and mood disturbance in chronic pain patients.

The results suggest that sleep disturbance is a prevalent complaint in chronic pain patients, but it is not always associated with an underlying mood disturbance.

The association of sleep and pain: an update and a path forward.

Evaluating Evidence for the Role of Sleep in Fibromyalgia: A Test of the Sleep and Pain Diathesis Model

A preliminary test of the SAPD model using cross-sectional data shows that FM patients who reported more disrupted sleep also reported higher levels of psychological disability and physical disability, and the relationship between sleep and disability appears to be mediated via pain.

The epidemiology of insomnia: associations with physical and mental health. The HUNT-2 study.

Sleep loss and REM sleep loss are hyperalgesic.

These studies showed that the loss of 4 hours of sleep and specific REM sleep loss are hyperalgesic the following day, implying that pharmacologic treatments and clinical conditions that reduce sleep and REM sleep time may increase pain.

The effect of sleep deprivation on pain.

Experimental human and animal studies on the effects of sleep deprivation on pain processing were reviewed and the significance of opioidergic and serotoninergic processes as mediating mechanisms of the hyperalgesic changes produced by sleep deprivation are discussed.

The effects of total sleep deprivation, selective sleep interruption and sleep recovery on pain tolerance thresholds in healthy subjects

The analgesic effect of SWS recovery is apparently greater than the analgesia induced by level I (World Health Organization) analgesic compounds in mechanical pain experiments in healthy volunteers.