Sleep and inflammation: partners in sickness and in health

  title={Sleep and inflammation: partners in sickness and in health},
  author={Michael R. Irwin},
  journal={Nature Reviews Immunology},
  • M. Irwin
  • Published 1 November 2019
  • Biology, Psychology
  • Nature Reviews Immunology
The discovery of reciprocal connections between the central nervous system, sleep and the immune system has shown that sleep enhances immune defences and that afferent signals from immune cells promote sleep. One mechanism by which sleep is proposed to provide a survival advantage is in terms of supporting a neurally integrated immune system that might anticipate injury and infectious threats. However, in modern times, chronic social threats can drive the development of sleep disturbances in… 

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