Sleep and Human Aging

  title={Sleep and Human Aging},
  author={Bryce A. Mander and Joseph R. Winer and Matthew P. Walker},

Figures from this paper

Do Older Adults Need Sleep? A Review of Neuroimaging, Sleep, and Aging Studies

  • M. Scullin
  • Psychology, Biology
    Current Sleep Medicine Reports
  • 2017
Older adults need sleep, but cortical thinning and amyloidal deposition with advancing age may weaken the brain’s ability to produce restorative sleep, and sleep in older adults may not always support identical functions for physical, mental, and cognitive health as in young adults.

Sleep Deficiency in the Elderly

Memory-relevant nap sleep physiology in healthy and pathological aging.

Interventions targeted at improving sleep physiology may help to reduce memory decline in both groups, but the results indicate changes in nap sleep physiology and sleep-related memory consolidation in older adults with and without MCI.

Sleep in the Aging Brain

This editorial paper summarizes the present knowledge about the main aging-related sleep modifications and their relevance for health problems and cognitive decline and presents the papers published in the Special Issue “Disturbances of Sleep Among Older People”.

Sleep and ageing: from human studies to rodent models

Sleep in Normal Aging, Homeostatic and Circadian Regulation and Vulnerability to Sleep Deprivation

The understanding of the respective contribution of circadian and homeostatic processes in the regulation of neurobehavioral function with aging present a challenge for improving health, management of cognitive decline and potential early chronobiological or sleep-wake interventions.

Dynamic Contributions of Slow Wave Sleep and REM Sleep to Cognitive Longevity

It is contended that preserved or enhanced REM sleep may compensate for otherwise disrupted sleep in advancing age, and is proposed that a more fruitful approach for future work will be to investigate how REM and slow wave processes dynamically interact to affect cognitive longevity.

Later-life sleep, cognition, and neuroimaging research: an update for 2020

Age and Race-Related Differences in Sleep Discontinuity Linked to Associative Memory Performance and Its Neural Underpinnings

It was found that more variable sleep quality was associated with worse memory performance, particularly for older adults, and greater sleep variation, that is evident in Black adults, may hamper memory-related neural function.



Sleep, Cognition, and Normal Aging

  • M. ScullinD. Bliwise
  • Psychology
    Perspectives on psychological science : a journal of the Association for Psychological Science
  • 2015
The literature is interpreted as suggesting that maintaining good sleep quality, at least in young adulthood and middle age, promotes better cognitive functioning and serves to protect against age-related cognitive declines.

Sleep, memory, and aging: the link between slow-wave sleep and episodic memory changes from younger to older adults.

The findings suggest that the link between episodic memory and SWS that is typically observed in younger adults may be weakened or otherwise changed in the healthy older adult population.

Recent Advances in Understanding Sleep and Sleep Disturbances in Older Adults

The growing understanding of how sleep changes with aging and of the causes of these changes is informing ever-improving treatments for these disturbances, thereby helping to ensure that growing older does not mean sleeping poorly.

Sleep protects memories from interference in older adults

Age-Related Reduction in the Maximal Capacity for Sleep—Implications for Insomnia

Is there a link between sleep changes and memory in Alzheimer's disease?

These results are the first report of a specific decrease in fast spindles in AD, associated with learning abilities, and give further hints for a functional differentiation between slow and fast spINDles.

fMRI and sleep correlates of the age‐related impairment in motor memory consolidation

The findings suggest that the deficit in sleep‐dependent motor memory consolidation in elderly individuals is related to a reduction in sleep spindle oscillations and to an associated decrease of activity in the cortico‐striatal network.

Age-related decline of sleep-dependent consolidation.

Older adults showed similar degrees of initial learning, however, performance of the older adults did not improve following sleep, providing evidence that sleep-dependent consolidation is diminished with age.

Midlife decline in declarative memory consolidation is correlated with a decline in slow wave sleep.

A decline in sleep-associated declarative memory consolidation that develops already during midlife and is associated with a decrease in early nocturnal SWS is indicated.

Prefrontal neuropsychological effects of sleep deprivation in young adults--a model for healthy aging?

It was concluded that 36h SD in young adults produces effects on the PFC similar to those found in normal, alert people aged about 60 years, however, it can not be concluded that an aged brain is a sleep-deprived brain.