Sleep Deprivation Impairs Consolidation of Cued Fear Memory in Rats

@inproceedings{Kumar2012SleepDI,
  title={Sleep Deprivation Impairs Consolidation of Cued Fear Memory in Rats},
  author={T. M. Sunil Kumar and Sushil K Jha},
  booktitle={PloS one},
  year={2012}
}
Post-learning sleep facilitates negative memory consolidation and also helps preserve it over several years. It is believed, therefore, that sleep deprivation may help prevent consolidation of fearful memory. Its effect, however, on consolidation of negative/frightening memories is not known. Cued fear-conditioning (CuFC) is a widely used model to understand the neural basis of negative memory associated with anxiety disorders. In this study, we first determined the suitable circadian timing… CONTINUE READING