Review of the extant literature indicates that both sleep apnea and glaucoma are highly prevalent in the Black population [1,2]. They tend to occur earlier among Blacks and are associated with other metabolic diseases (e.g., obesity and hypertension). that are also highly prevalent in that ethnic group [3,4]. While technology for early detection and evidence-based treatment regimens exist for sleep apnea and glaucoma, sadly Blacks underuse them. Consequently, Blacks in underserved communities continue to bear the burden of those conditions, which have remained largely undiagnosed [5,6]. Whereas prevalence data convincingly show the risks for expressing sleep apnea and glaucoma are higher among Blacks, they are, nevertheless, not as likely to seek medical care as do Whites, even where there is no disparity in adequate medical coverage . Effort should be made to explore the reasons why so few Blacks participate in sleep apnea or ophthalmic screening programs or are receiving timely diagnoses [8,9]. This paper attempts to provide background information supporting greater prevalence of glaucoma and sleep apnea for Blacks in the US. Furthermore, it suggests that if these two conditions were causally associated Blacks would be at greater risk for related comorbidities.