Sleep, memory, and plasticity.

@article{Walker2006SleepMA,
  title={Sleep, memory, and plasticity.},
  author={Matthew P. Walker and Robert Stickgold},
  journal={Annual review of psychology},
  year={2006},
  volume={57},
  pages={
          139-66
        }
}
Although the functions of sleep remain largely unknown, one of the most exciting hypotheses is that sleep contributes importantly to processes of memory and brain plasticity. Over the past decade, a large body of work, spanning most of the neurosciences, has provided a substantive body of evidence supporting this role of sleep in what is becoming known as sleep-dependent memory processing. We review these findings, focusing specifically on the role of sleep in (a) memory encoding, (b) memory… 

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References

SHOWING 1-10 OF 129 REFERENCES

Sleep-Dependent Learning and Memory Consolidation

The REM Sleep-Memory Consolidation Hypothesis

TLDR
The evidence for the hypothesis that REM (rapid eye movement) sleep has an important role in memory consolidation is reviewed and found to be weak and contradictory.

A refined model of sleep and the time course of memory formation.

  • M. Walker
  • Biology, Psychology
    The Behavioral and brain sciences
  • 2005
TLDR
A new neurocognitive framework of procedural learning is offered, consisting first of acquisition, followed by two specific stages of consolidation, one involving a process of stabilization, the other involving enhancement, whereby delayed learning occurs.

REM sleep and memory consolidation

Memory consolidation and reconsolidation: what is the role of sleep?

The cognitive neuroscience of sleep: neuronal systems, consciousness and learning

TLDR
This work discusses neuronal-network and regional forebrain activity during sleep, and its consequences for consciousness and cognition, and indicates possible roles for sleep in neuroplasticity.

Local sleep and learning

TLDR
It is shown that sleep homeostasis indeed has a local component, which can be triggered by a learning task involving specific brain regions, and that the local increase in SWA after learning correlates with improved performance of the task after sleep.

Sleep Deprivation Causes Behavioral, Synaptic, and Membrane Excitability Alterations in Hippocampal Neurons

TLDR
The exposure of rats to 72 hr of primarily rapid eye movement SD impaired their subsequent performance on a hippocampus-dependent spatial learning task but had no effect on an amygdala-dependent learning task, suggesting that failure to acquire adequate sleep produces several molecular and cellular level alterations that profoundly inhibit hippocampal functioning.

Low acetylcholine during slow-wave sleep is critical for declarative memory consolidation

  • S. GaisJ. Born
  • Biology, Psychology
    Proceedings of the National Academy of Sciences of the United States of America
  • 2004
TLDR
Increasing central nervous cholinergic activation during SWS-rich sleep by posttrial infusion of 0.75 mg of the cholinesterase inhibitor physostigmine completely blocked SWs-related consolidation of declarative memories for word pairs in human subjects, in line with predictions that a low Cholinergic tone duringSWS is essential forDeclarative memory consolidation.
...