Slc26a4 expression prevents fluctuation of hearing in a mouse model of large vestibular aqueduct syndrome.

Abstract

SLC26A4 mutations cause fluctuating and progressive hearing loss associated with enlargement of the vestibular aqueduct (EVA). SLC26A4 encodes a transmembrane anion exchanger called pendrin expressed in nonsensory epithelial cells of the lateral wall of cochlea, vestibular organs and endolymphatic sac. We previously described a transgenic mouse model of EVA… (More)
DOI: 10.1016/j.neuroscience.2016.04.042

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