Sla2p is associated with the yeast cortical actin cytoskeleton via redundant localization signals.

@article{Yang1999Sla2pIA,
  title={Sla2p is associated with the yeast cortical actin cytoskeleton via redundant localization signals.},
  author={Shuwu Yang and M. Jamie T. V. Cope and David G Drubin},
  journal={Molecular biology of the cell},
  year={1999},
  volume={10 7},
  pages={
          2265-83
        }
}
Sla2p, also known as End4p and Mop2p, is the founding member of a widely conserved family of actin-binding proteins, a distinguishing feature of which is a C-terminal region homologous to the C terminus of talin. These proteins may function in actin cytoskeleton-mediated plasma membrane remodeling. A human homologue of Sla2p binds to huntingtin, the protein whose mutation results in Huntington's disease. Here we establish by immunolocalization that Sla2p is a component of the yeast cortical… CONTINUE READING

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