Skin reactivity to inhalant allergens, total serum IgE levels, and bronchial responsiveness to methacholine are increased in parents of nonatopic asthmatic children.

Abstract

BACKGROUND Family studies suggest that asthma has an increased familial occurrence, but the hypothesis of a genetic predisposition to IgE response and bronchial hyperresponsiveness (BHR) on the expression of nonatopic asthma is controversial. OBJECTIVE The aim of this study was to evaluate familial predisposition to IgE response and BHR on expression of… (More)

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@article{Kim1999SkinRT, title={Skin reactivity to inhalant allergens, total serum IgE levels, and bronchial responsiveness to methacholine are increased in parents of nonatopic asthmatic children.}, author={Y. K. Kim and S. H. Cho and Young Yull Koh and Ji Woong Son and Y. K. Jee and M. H. Lee and K. U. Min and Y. Y. Kim}, journal={The Journal of allergy and clinical immunology}, year={1999}, volume={104 2 Pt 1}, pages={311-6} }