Skin reactions to intradermal neuromuscular blocking agent injections: a randomized multicenter trial in healthy volunteers.

@article{Mertes2007SkinRT,
  title={Skin reactions to intradermal neuromuscular blocking agent injections: a randomized multicenter trial in healthy volunteers.},
  author={Paul Michel Mertes and Denise Anne Moneret-Vautrin and Francisque Leynadier and M Laxenaire},
  journal={Anesthesiology},
  year={2007},
  volume={107 2},
  pages={245-52}
}
BACKGROUND Numerous reports confirm the performance of intradermal tests for the diagnosis of anaphylaxis during anesthesia; however, there is controversy over their diagnostic value regarding the newer neuromuscular blocking agents (NMBAs). METHODS One hundred eleven healthy volunteers were randomly assigned to receive intradermal injections of two NMBAs, at five increasing concentrations. A concentration was considered as a reactive concentration when it led to a positive reaction in more… CONTINUE READING

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