Skin reaction in antiviral therapy for chronic hepatitis C: a role for polyethylene glycol interferon?

@article{Cottoni2004SkinRI,
  title={Skin reaction in antiviral therapy for chronic hepatitis C: a role for polyethylene glycol interferon?},
  author={Francesca Cottoni and Silvia Bolognini and Angelo Deplano and Giovanni Garrucciu and Noemi Elisabetta Manzoni and Giovanna Francesca Careddu and Maria Antonia Montesu and Andreina Tocco and Amelia Lissia and Antonio Solinas},
  journal={Acta dermato-venereologica},
  year={2004},
  volume={84 2},
  pages={120-3}
}
In the past decade, different modalities of antiviral therapy have been adopted aimed at eradicating hepatitis C virus infection. Initially, interferon was used in monotherapy, then interferon combined with ribavirin and amantadine. Recently, interferon has been conjugated with polyethylene glycol to allow optimization of its pharmacokinetic properties and to improve its antiviral activity. This study focused on the characteristics of the skin reactions that we observed in 27 patients with na… CONTINUE READING
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A randomized , double - blind trial comparing pegylated interferon alfa2 b to interferon a - 2 b as initial treatment for chronic hepatitis C

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