Skin pigmentation, biogeographical ancestry and admixture mapping

@article{Shriver2003SkinPB,
  title={Skin pigmentation, biogeographical ancestry and admixture mapping},
  author={Mark David Shriver and Esteban Juan Parra and Sonia Dios and Carolina Bonilla and Heather L. Norton and Celina Jovel and Carrie Lynn Pfaff and Cecily Jones and Aisha Massac and Neil Cameron and Archie Baron and Tabitha Jackson and George Argyropoulos and Li Jin and Clive J. Hoggart and Paul M. McKeigue and Rick A. Kittles},
  journal={Human Genetics},
  year={2003},
  volume={112},
  pages={387-399}
}
Ancestry informative markers (AIMs) are genetic loci showing alleles with large frequency differences between populations. AIMs can be used to estimate biogeographical ancestry at the level of the population, subgroup (e.g. cases and controls) and individual. Ancestry estimates at both the subgroup and individual level can be directly instructive regarding the genetics of the phenotypes that differ qualitatively or in frequency between populations. These estimates can provide a compelling… Expand
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