Skin pH: from basic science to basic skin care.

  title={Skin pH: from basic science to basic skin care.},
  author={Saba M Ali and Gil Yosipovitch},
  journal={Acta dermato-venereologica},
  volume={93 3},
The "acid mantle" is a topic not only of historical interest, but also of clinical significance and has recently been linked to vital stratum corneum function. Despite compelling basic science evidence placing skin pH as a key factor in barrier homeostasis, stratum corneum integrity, and antimicrobial defense, application of the acid mantle concept in clinical care is lacking. We review recent basic science investigations into skin pH, discuss skin disorders characterized by aberrant pH, and… CONTINUE READING