Skin graft vascularization involves precisely regulated regression and replacement of endothelial cells through both angiogenesis and vasculogenesis.

@article{Capla2006SkinGV,
  title={Skin graft vascularization involves precisely regulated regression and replacement of endothelial cells through both angiogenesis and vasculogenesis.},
  author={Jennifer M. Capla and Daniel J Ceradini and Oren M. Tepper and Matthew J. Callaghan and Kirit R. Bhatt and Robert D. Galiano and Jamie P. Levine and Geoffrey C Gurtner},
  journal={Plastic and reconstructive surgery},
  year={2006},
  volume={117 3},
  pages={
          836-44
        }
}
BACKGROUND Long-term survival of a skin graft is dependent on eventual revascularization. The authors' aim in the present study was to determine whether skin graft vascularization occurs by (1) simple reconnection of vessels, (2) ingrowth of recipient vasculature, (3) outgrowth of donor-derived vessels, and/or (4) recruitment of bone marrow-derived endothelial progenitor cells. METHODS Full-thickness skin grafts (1 x 1 cm) were transferred between wild-type FVB/N mice (n = 20) and transgenic… CONTINUE READING

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