Skin-derived fibroblasts respond to human parathyroid hormone-like adenylate cyclase-stimulating proteins.

@article{Wu1987SkinderivedFR,
  title={Skin-derived fibroblasts respond to human parathyroid hormone-like adenylate cyclase-stimulating proteins.},
  author={Tianyun Wu and Karl L. Insogna and L M Hough and Leonard M. Milstone and Andrew Francis Stewart},
  journal={The Journal of clinical endocrinology and metabolism},
  year={1987},
  volume={65 1},
  pages={105-9}
}
Human tumors and keratinocyte-conditioned medium contain PTH-like adenylate cyclase-stimulating proteins. Human dermal fibroblasts have receptors that recognize PTH and a factor associated with humoral hypercalcemia of malignancy in rats. We examined 10 human dermal fibroblast lines for an adenylate cyclase response to PTH. Six of 10 lines tested displayed… CONTINUE READING