Skin cancer treatment by albumin/5-Fu loaded magnetic nanocomposite spheres in a mouse model.

@article{Misak2013SkinCT,
  title={Skin cancer treatment by albumin/5-Fu loaded magnetic nanocomposite spheres in a mouse model.},
  author={Heath Misak and Niki Zacharias and Zhitao Song and Shiaw-Min Hwang and K-P Man and Ramazan Asmatulu and S Yang},
  journal={Journal of biotechnology},
  year={2013},
  volume={164 1},
  pages={130-6}
}
Albumin/drug loaded magnetic nanocomposite spheres were fabricated using an oil-in-oil emulsion/solvent evaporation method, and tested on a mouse model (experimental squamous cell carcinoma) to determine the efficacy of the drug delivery system (DDS) on skin cancer. This novel DDS consists of human serum albumin, poly(lactic-co-glycolic acid) (PLGA), 5-fluorouracil (5-Fu), magnetic nanoparticles (10 nm) and fluorescent labeling molecule (diphenylhexatriene). One of the major purposes of using… CONTINUE READING