Skin biopsy for assessment of autonomic denervation in Parkinson’s disease

@article{Dabby2005SkinBF,
  title={Skin biopsy for assessment of autonomic denervation in Parkinson’s disease},
  author={Ron Dabby and Ruth Djaldetti and Mark Shahmurov and Therese A. Treves and B. Gabai and Eldad Melamed and Menachem Sadeh and Ilana Avinoach},
  journal={Journal of Neural Transmission},
  year={2005},
  volume={113},
  pages={1169-1176}
}
Autonomic dysfunction in Parkinson’s disease (PD) is considered a late complication of the disease or an adverse effect of anti-parkinsonian medications. Morphological changes are demonstrated only by postmortem examination. The study objective was to evaluate peripheral autonomic neural involvement in PD using punch skin biopsy. The study sample included 22 patients (mean age 50 ± 7.7 years, mean disease duration 5.3 ± 3.8 years) and 19 controls. Four-millimeter skin biopsies were… CONTINUE READING
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