Skin antioxidants: their role in aging and in oxidative stress--new approaches for their evaluation.

@article{Kohen1999SkinAT,
  title={Skin antioxidants: their role in aging and in oxidative stress--new approaches for their evaluation.},
  author={Ron Kohen},
  journal={Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie},
  year={1999},
  volume={53 4},
  pages={
          181-92
        }
}
Skin is a highly metabolic tissue which possesses the largest surface area in the body and serves as the protective layer for internal organs [1]. Skin is also a major candidate and target of oxidative stress. It is designed to give both physical and biochemical protection, and is equipped with a large number of defense mechanisms. The skin tissue is exposed to a variety of damaging species which originate in the outer environment, in the skin itself, and in various endogenous sources [2, 3… CONTINUE READING
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