Skin Heating and Injury by Prolonged Millimeter-Wave Exposure: Theory Based on a Skin Model Coupled to a Whole Body Model and Local Biochemical Release From Cells at Supraphysiologic Temperatures

@article{Stewart2006SkinHA,
  title={Skin Heating and Injury by Prolonged Millimeter-Wave Exposure: Theory Based on a Skin Model Coupled to a Whole Body Model and Local Biochemical Release From Cells at Supraphysiologic Temperatures},
  author={Donald A. Stewart and T R Gowrishankar and James C. Weaver},
  journal={IEEE Transactions on Plasma Science},
  year={2006},
  volume={34},
  pages={1480-1493}
}
Energy dissipation by millimeter-wavelength electromagnetic-radiation (MMW; f~3-300 GHz) exposure to mammalian skin occurs within the outer surface. The penetration depth is less than 1 mm for frequencies above 25 GHz. A transport-lattice system model is used, which incorporates two spatial scales to estimate heat and chemical transport in rat skin in vivo: 1) a layered skin model involving the outer several millimeters of the body coupled to 2) a whole body model. The whole body model accounts… 

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References

SHOWING 1-10 OF 51 REFERENCES

INTER-SPECIES EXTRAPOLATION OF SKIN HEATING RESULTING FROM MILLIMETER WAVE IRRADIATION: MODELING AND EXPERIMENTAL RESULTS

Results suggest a variable blood flow model, reflecting a dynamic thermoregulatory response, may be more suited to describing skin surface temperature response under long-duration MMW irradiation.

EFFECTS OF BLOOD FLOW ON SKIN HEATING INDUCED BY MILLIMETER WAVE IRRADIATION IN HUMANS

The results of these studies demonstrate that relatively small changes in skin blood flow may produce substantial alterations in the rate of skin heating during prolonged 94-GHz exposure.

Heating and pain sensation produced in human skin by millimeter waves: comparison to a simple thermal model.

The measured increases in surface temperature were in good agreement with a simple thermal model that accounted for heat conduction and for the penetration depth of the microwave energy into tissue, and support the use of the model for predicting thresholds of thermal pain at other millimeter wave (length) frequencies.

Thermal models for microwave hazards and their role in standards development.

It is concluded that thermal models are a potentially fruitful but underutilized means of analyzing thermal hazards from RF fields, and a quantitative analysis of such hazards enables the development of data-based uncertainty factors, which can replace arbitrary "safety factors" in developing exposure limits.

Modeling thermal responses in human subjects following extended exposure to radiofrequency energy

The model was most successful in predicting changes in skin temperature, and it provides insights into the mechanisms by which the heat added to body by RF energy is dissipated to the environment.

Cardiovascular and thermal responses in rats during 94 GHz irradiation.

It is concluded that exposure to 94 GHz RFR produces extreme peripheral heating without similar levels of core heating and that this pattern of heat deposition is sufficient to produce circulatory failure and subsequent death.

Heating patterns in biological tissue phantoms caused by millimeter wave electromagnetic irradiation

It was found that horn antennas produced nonuniform heating patterns in irradiated objects due to a geometrical resonance resulting from a secondary wave-mode interaction between an irradiated object and the corresponding critical cross-section of the horn antenna.

SUSTAINED 35‐GHz RADIOFREQUENCY IRRADIATION INDUCES CIRCULATORY FAILURE

Analysis of thermal distribution and cardiovascular changes produced by whole-body exposure of ketamine-anesthetized rats to radiofrequency radiation of millimeter wave (MMW) length indicates that circulatory failure and subsequent death may occur when skin temperature is rapidly elevated, even in the presence of relatively normal Tc.

THERMAL MODELING OF MILLIMETER WAVE DAMAGE TO THE PRIMATE CORNEA AT 35 GHz AND 94 GHz

The measured temperature increases during the exposures agree with the model within the variability of the data, and thresholds for thermal damage to the cornea can be predicted for a range of exposure conditions.

Radio frequency radiation of millimeter wave length: potential occupational safety issues relating to surface heating.

This review attempts to critically analyze the likelihood of such acute effects as burn and eye damage, as well as potential long-term effects, including cancer, associated with accidental overexposure to MMWs.
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