Skin Color Variation in Orang Asli Tribes of Peninsular Malaysia

@inproceedings{Ang2012SkinCV,
  title={Skin Color Variation in Orang Asli Tribes of Peninsular Malaysia},
  author={Khai Chung Ang and Mee Siing Ngu and Katherine P. Reid and Mei S. Teh and Zamzuraida S. Aida and Danny XR. Koh and Arthur Berg and Stephen Oppenheimer and Hood Salleh and Mahani Mansor Clyde and Badrul Munir Md-Zain and Victor A. Canfield and Keith C. Cheng},
  booktitle={PloS one},
  year={2012}
}
Pigmentation is a readily scorable and quantitative human phenotype, making it an excellent model for studying multifactorial traits and diseases. Convergent human evolution from the ancestral state, darker skin, towards lighter skin colors involved divergent genetic mechanisms in people of European vs. East Asian ancestry. It is striking that the European mechanisms result in a 10-20-fold increase in skin cancer susceptibility while the East Asian mechanisms do not. Towards the mapping of… CONTINUE READING