Skilled forelimb use in the rat: amelioration of functional deficits resulting from neonatal damage to the frontal cortex by neonatal transplantation of fetal cortical tissue.

@article{Plumet1991SkilledFU,
  title={Skilled forelimb use in the rat: amelioration of functional deficits resulting from neonatal damage to the frontal cortex by neonatal transplantation of fetal cortical tissue.},
  author={Joaqu{\'i}n Plumet and J. Cadusseau and M. Roger},
  journal={Restorative neurology and neuroscience},
  year={1991},
  volume={3 3},
  pages={135-47}
}
Limb preference and dexterity of right and left forelimbs were studied in a food reaching task in normal rats (control group), in rats that sustained a neonatal lesion of the left frontal cortex (lesion group) and in animals that received a transplant obtained from the frontal cortex of 16-day-old embryos immediately after the lesion (graft group). In addition, an anatomical study of host-transplant interconnections was performed in several transplanted animals. The results indicate that the… CONTINUE READING
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