Skew in the human caveolin 1 gene upstream purine complex homozygote haplotype compartment in multiple sclerosis

@article{Yeganeh2009SkewIT,
  title={Skew in the human caveolin 1 gene upstream purine complex homozygote haplotype compartment in multiple sclerosis},
  author={Marjan Zarif Yeganeh and Majid Ghaffarpour and D D Farhud and Masoud Karimlou and Mandana Ohadi},
  journal={Journal of Neuroimmunology},
  year={2009},
  volume={216},
  pages={103-107}
}
Caveolin 1 (CAV1) is a component of the myelin sheath and the expression of the gene encoding this protein is increased during myelination in Schwann cells and oligodendrocytes. We sought to investigate the homozygote haplotype compartment in a recently identified polymorphic purine complex at the upstream region of the human CAV1 gene in multiple sclerosis (MS). In a case/control study design, the region was characterized in 126 cases of MS diagnosed based on the Revised McDonald diagnostic… CONTINUE READING

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