Skeletal trauma generates systemic BMP2 activation that is temporally related to the mobilization of CD73+ cells

Abstract

The relationship between BMP2 expression and the recruitment of skeletogenic stem cells was assessed following bone marrow reaming. BMP2 expression was examined using transgenic mice in which β-galactosidase had been inserted into the coding region of BMP2. Stem cell mobilization was analyzed by FACS analysis using CD73, a marker associated with bone marrow… (More)
DOI: 10.1002/jor.22487

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