Skeletal responsiveness to parathyroid hormone in healthy females: relationship to menopause and oestrogen replacement.

@article{Joborn1991SkeletalRT,
  title={Skeletal responsiveness to parathyroid hormone in healthy females: relationship to menopause and oestrogen replacement.},
  author={Charlotte Joborn and Sverker Ljunghall and Karin Larsson and Erik Lindh and Tord Naess{\'e}n and Leif Wide and G{\"o}ran {\AA}kerstr{\"o}m and Jonas Rastad},
  journal={Clinical endocrinology},
  year={1991},
  volume={34 5},
  pages={335-9}
}
In order to directly evaluate the role of parathyroid hormone (PTH) and its interaction with oestrogens for postmenopausal bone loss, studies were performed where synthetic human (1-38) PTH was infused s.c. over 24 h in 15 healthy females. Measurements were made of serum electrolytes, PTH and biochemical indices of bone turnover: serum osteocalcin and alkaline phosphatase and fasting urinary hydroxyproline and calcium. During the infusion of PTH there were significant increases of serum calcium… CONTINUE READING

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