Skeletal muscle myosin heavy chain synthesis in type 1 diabetes.

@article{Charlton1997SkeletalMM,
  title={Skeletal muscle myosin heavy chain synthesis in type 1 diabetes.},
  author={Michael R. Charlton and Prabhakaran Balagopal and K. Sreekumaran Nair},
  journal={Diabetes},
  year={1997},
  volume={46 8},
  pages={1336-40}
}
Although insulin's anticatabolic effect on protein metabolism in type 1 diabetes has been clearly shown to be related to the inhibition of protein breakdown, insulin's effect on muscle protein synthesis remains controversial. Cross-limb studies and measurements of synthesis rates of mixed muscle protein have yielded conflicting results. These measurements… CONTINUE READING