Skeletal muscle mitochondrial density, gene expression, and enzyme activities in human heart failure: minimal effects of the disease and resistance training.

@article{Toth2012SkeletalMM,
  title={Skeletal muscle mitochondrial density, gene expression, and enzyme activities in human heart failure: minimal effects of the disease and resistance training.},
  author={Michael J. Toth and Mark S. Miller and Kimberly A Ward and Philip A. Ades},
  journal={Journal of applied physiology},
  year={2012},
  volume={112 11},
  pages={1864-74}
}
Impaired skeletal muscle energetics could adversely affect physical and metabolic function in patients with heart failure (HF). The effect of HF on aspects of mitochondrial structure and function, independent of muscle disuse and other disease-related confounding factors, however, is unclear. Moreover, no study has evaluated whether resistance exercise training, a modality that increases functional capacity, might derive its benefits through modulation of mitochondrial structure and function… CONTINUE READING

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