Skeletal muscle mitochondria: a major player in exercise, health and disease.

@article{Russell2014SkeletalMM,
  title={Skeletal muscle mitochondria: a major player in exercise, health and disease.},
  author={Aaron P Russell and Victoria C. Foletta and Rod J. Snow and Glenn D Wadley},
  journal={Biochimica et biophysica acta},
  year={2014},
  volume={1840 4},
  pages={1276-84}
}
BACKGROUND Maintaining skeletal muscle mitochondrial content and function is important for sustained health throughout the lifespan. Exercise stimulates important key stress signals that control skeletal mitochondrial biogenesis and function. Perturbations in mitochondrial content and function can directly or indirectly impact skeletal muscle function and consequently whole-body health and wellbeing. SCOPE OF REVIEW This review will describe the exercise-stimulated stress signals and… CONTINUE READING

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Pharmacological manipulation of exercise - induced pathways that increase skeletal muscle mitochondrial biogenesis and function in critically ill patients , where exercise may not be possible , may assist in the treatment of chronic disease .
Pharmacological manipulation of exercise - induced pathways that increase skeletal muscle mitochondrial biogenesis and function in critically ill patients , where exercise may not be possible , may assist in the treatment of chronic disease .
It will then discuss the major myopathies , neuromuscular diseases and conditions such as diabetes and ageing that have dysregulated mitochondrial function .
It will then discuss the major myopathies , neuromuscular diseases and conditions such as diabetes and ageing that have dysregulated mitochondrial function .
It will then discuss the major myopathies , neuromuscular diseases and conditions such as diabetes and ageing that have dysregulated mitochondrial function .
It will then discuss the major myopathies , neuromuscular diseases and conditions such as diabetes and ageing that have dysregulated mitochondrial function .
It will then discuss the major myopathies , neuromuscular diseases and conditions such as diabetes and ageing that have dysregulated mitochondrial function .
It will then discuss the major myopathies , neuromuscular diseases and conditions such as diabetes and ageing that have dysregulated mitochondrial function .
It will then discuss the major myopathies , neuromuscular diseases and conditions such as diabetes and ageing that have dysregulated mitochondrial function .
It will then discuss the major myopathies , neuromuscular diseases and conditions such as diabetes and ageing that have dysregulated mitochondrial function .
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